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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

A metagenomic snapshot of taxonomic and functional diversity in an ...
Published: September, 2013
Abstract: Cryoconite is a microbe–mineral aggregate which darkens the ice surface of glaciers. Microbial process and marker gene PCR-dependent measurements r... Read more »
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DNA shearing Bioruptor
Epigenetic silencing of Bim transcription by Spi-1/PU.1 promotes ap...
Published: September, 2013
Abstract: Deregulation of transcriptional networks contributes to haematopoietic malignancies. The transcription factor Spi-1/PU.1 is a master regulator of h... Read more »
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DNA shearing Bioruptor MeDIP kit
Mass production of SNP markers in a nonmodel passerine bird through...
Published: September, 2013
Abstract: Here, we present an adaptation of restriction-site-associated DNA sequencing (RAD-seq) to the Illumina HiSeq2000 technology that we used to produce... Read more »
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DNA shearing Bioruptor
Let-7b and miR-495 Stimulate Differentiation and Prevent Metaplasia...
Published: September, 2013
Abstract: BACKGROUND & AIMS: Diseases of the exocrine pancreas are often associated with perturbed differentiation of acinar cells. MicroRNAs (miRNAs) regula... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The ASAP2 gene is a primary target of 1,25-dihydroxyvitamin D3 in h...
Published: August, 2013
Abstract: A genome-wide data set on vitamin D receptor (VDR) binding sites in human THP-1 cells (monocytes) led us to the genomic region around the ASAP2 (Ar... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
Long range epigenetic silencing is a trans-species mechanism that r...
Published: August, 2013
Abstract: DNA methylation and chromatin remodeling are frequently implicated in the silencing of genes involved in carcinogenesis. Long Range Epigenetic Sile... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody LowCell ChIP kit
Endogenous Nuclear RNAi Mediates Behavioral Adaptation to Odor.
Published: August, 2013
Abstract: Most eukaryotic cells express small regulatory RNAs. The purpose of one class, the somatic endogenous siRNAs (endo-siRNAs), remains unclear. Here, ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Transcriptional environment and chromatin architecture interplay di...
Published: August, 2013
Abstract: To explore the response of β globin locus with established chromatin domains upon their exposure to new transcriptional environments, we transferre... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
PRC2 Controls Drosophila Oocyte Cell Fate by Repressing Cell Cycle ...
Published: August, 2013
Abstract: The oocyte is a unique cell type that undergoes extensive chromosome changes on its way to fertilization, but the chromatin determinants of its fat... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Proteomics Strategies to Identify SUMO Targets and Acceptor Sites: ...
Published: August, 2013
Abstract: SUMOylation is a protein posttranslational modification that participates in the regulation of numerous biological processes within the cells. Smal... Read more »
A signature motif mediating selective interactions of BCL11A with t...
Published: August, 2013
Abstract: Despite their physiological importance, selective interactions between nuclear receptors (NRs) and their cofactors are poorly understood. Here, we ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Enhanced Chromatin Dynamics by FACT Promotes Transcriptional Restar...
Published: August, 2013
Abstract: Chromatin remodeling is tightly linked to all DNA-transacting activities. To study chromatin remodeling during DNA repair, we established quantitat... Read more »
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Bioruptor Chromatin Shearing
Optical control of mammalian endogenous transcription and epigeneti...
Published: August, 2013
Abstract: The dynamic nature of gene expression enables cellular programming, homeostasis and environmental adaptation in living systems. Dissection of causa... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
A GAA repeat expansion reporter model of Friedreich's ataxia recapi...
Published: August, 2013
Abstract: Friedreich's ataxia (FRDA) is caused by large GAA expansions in intron 1 of the frataxin gene (FXN), which lead to reduced FXN expression through a... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Conserved Regulators of Nucleolar Size Revealed by Global Phenotypi...
Published: August, 2013
Abstract: Regulation of cell growth is a fundamental process in development and disease that integrates a vast array of extra- and intracellular information.... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Sexually Dimorphic Genome-Wide Binding of Retinoid X Receptor alpha...
Published: August, 2013
Abstract: Many hepatic functions including lipid metabolism, drug metabolism, and inflammatory responses are regulated in a sex-specific manner due to distin... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
PARP-1 Controls Immunosuppressive Function of Regulatory T Cells by...
Published: August, 2013
Abstract: Poly (ADP-ribose) polymerase-1 (PARP-1) is a nuclear enzyme and transcription factor that is involved in inflammatory response, but its role in T c... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
An In-Depth Characterization of the Major Psoriasis Susceptibility ...
Published: August, 2013
Abstract: Psoriasis is an immune-mediated skin disorder that is inherited as a complex genetic trait. Although genome-wide association scans (GWAS) have iden... Read more »
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Antibody
Genome-wide screening identifies Plasmodium chabaudi-induced modifi...
Published: August, 2013
Abstract: Epigenetic reprogramming of host genes via DNA methylation is increasingly recognized as critical for the outcome of diverse infectious diseases, b... Read more »
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Antibody MeDIP kit 5mC (C15200081)
Mutant IDH1 promotes leukemogenesis in vivo and can be specifically...
Published: August, 2013
Abstract: Mutations in the metabolic enzymes isocitrate dehydrogenase 1 (IDH1) and 2 (IDH2) are frequently found in glioma, acute myeloid leukemia (AML), mel... Read more »
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Bioruptor Cell Lysis Mass Spectrometry
Systematic Identification of Proteins Binding to Chromatin-Embedded...
Published: August, 2013
Abstract: Chromatin posttranslational modifications (PTMs), including monoubiquitylation of histone H2B on lysine 120 (H2Bub1), play a major role in regulati... Read more »
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Bioruptor Cell Lysis
CDK8-Mediated STAT1-S727 Phosphorylation Restrains NK Cell Cytotoxi...
Published: August, 2013
Abstract: The transcription factor STAT1 is important in natural killer (NK) cells, which provide immediate defense against tumor and virally infected cells.... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
WT1 regulates the expression of inhibitory chemokines during heart ...
Published: August, 2013
Abstract: The embryonic epicardium is an important source of cardiovascular precursor cells and paracrine factors that are required for adequate heart format... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Mod5 protein binds to tRNA gene complexes and affects local transcr...
Published: August, 2013
Abstract: The tRNA gene-mediated (tgm) silencing of RNA polymerase II promoters is dependent on subnuclear clustering of the tRNA genes, but genetic analysis... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Artd1/Parp1 regulates reprogramming by transcriptional regulation o...
Published: August, 2013
Abstract: The recently established reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) by Takahashi and Yamanaka, represents a valuabl... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
A Kinase-Independent Function of CDK6 Links the Cell Cycle to Tumor...
Published: August, 2013
Abstract: In contrast to its close homolog CDK4, the cell cycle kinase CDK6 is expressed at high levels in lymphoid malignancies. In a model for p185(BCR-ABL... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody H3K4me3 (C15410003)
Chromatin-Bound IκBα Regulates a Subset of Polycomb Target Genes in...
Published: August, 2013
Abstract: IκB proteins are the primary inhibitors of NF-κB. Here, we demonstrate that sumoylated and phosphorylated IκBα accumulates in the nucleus of kerati... Read more »
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Bioruptor
A three-state model for the regulation of telomerase by TERRA and h...
Published: August, 2013
Abstract: Telomeres, the physical ends of eukaryotic chromosomes, are transcribed into telomeric repeat-containing RNA (TERRA), a large non-coding RNA, which... Read more »
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Bioruptor
Ezh1 and Ezh2 differentially regulate PSD-95 gene transcription in ...
Published: August, 2013
Abstract: Polycomb Repressive Complex 2 (PRC2) mediates transcriptional silencing by catalyzing histone H3 lysine 27 trimethylation (H3K27me3), but its role ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-...
Published: August, 2013
Abstract: DNA methylation is a heritable epigenetic modification involved in gene silencing, imprinting, and the suppression of retrotransposons. Global DNA ... Read more »
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DNA shearing Bioruptor MagMeDIP kit Antibody

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