Publications,References

Clozapine and sulpiride but not haloperidol or olanzapine activate ...
Published: September, 2008

Abstract: Cortical GABAergic dysfunction, a hallmark of both schizophrenia (SZ) and bipolar (BP) disorder pathophysiologies may relate to the hypermethylatio... Read more »

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Antibody

Regulation of DNA methylation activity through Dnmt3L promoter meth...
Published: September, 2008

Abstract: The genomic DNA is methylated by de novo methyltransferases Dnmt3a and Dnmt3b during early embryonic development. The establishment of appropriate ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Stem cell-specific epigenetic priming and B cell-specific transcrip...
Published: September, 2008

Abstract: Low-level expression of multiple lineage-specific genes is a hallmark of hematopoietic stem cells (HSCs). HSCs predominantly express genes specific... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

SUMO-modified Sp3 represses transcription by provoking local hetero...
Published: September, 2008

Abstract: Modification of many transcription factors including Sp3 and steroidogenic factor 1 with the small ubiquitin-like modifier (SUMO) is associated wit... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

The histone demethylase KDM5b/JARID1b plays a role in cell fate dec...
Published: September, 2008

Abstract: The histone demethylase lysine demethylase 5b (KDM5b) specifically demethylates lysine 4 of histone H3 (meH3K4), thereby repressing gene transcript... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

BACH1 is a specific repressor of HMOX1 that is inactivated by arsen...
Published: August, 2008

Abstract: Intracellular heme is a redox active molecule that can be detrimental to cells at high concentrations or under oxidizing conditions. To prevent acc... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Transcriptional regulation of autocrine IL-6 expression in multiple...
Published: August, 2008

Abstract: Multiple myeloma (MM) is an as to date incurable hematopoietic malignancy. The importance of Interleukin-6 (IL-6) as an autocrine growth factor for... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Regulation of p53 target gene expression by peptidylarginine deimin...
Published: August, 2008

Abstract: Histone Arg methylation has been correlated with transcriptional activation of p53 target genes. However, whether this modification is reversed to ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Rapid, transcription-independent loss of nucleosomes over a large c...
Published: July, 2008

Abstract: To efficiently transcribe genes, RNA Polymerase II (Pol II) must overcome barriers imposed by nucleosomes and higher-order chromatin structure. Man... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

LXR signaling couples sterol metabolism to proliferation in the acq...
Published: July, 2008

Abstract: Cholesterol is essential for membrane synthesis; however, the mechanisms that link cellular lipid metabolism to proliferation are incompletely unde... Read more »

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Master Mix

Nucleotide excision repair driven by the dissociation of CAK from T...
Published: July, 2008

Abstract: The transcription/DNA repair factor TFIIH is organized into a core that associates with the CDK-activating kinase (CAK) complex. Using chromatin im... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Recruitment of CREB1 and histone deacetylase 2 (HDAC2) to the mouse...
Published: June, 2008

Abstract: Latent TGFbeta-binding protein 1 (LTBP-1) is a key regulator of TGFbeta targeting and activation in the extracellular matrix. LTBP-1 is recognized ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Analysis of the Runx2 promoter in osseous and non-osseous cells and...
Published: June, 2008

Abstract: Little is known about the upstream regulator of Runx2, a master regulator of osteoblast differentiation in bone tissues. To elucidate the molecular... Read more »

Role of STAT3 in glucocorticoid-induced expression of the human IL-...
Published: June, 2008

Abstract: In the present report we have determined the molecular mechanisms, which govern the expression of the human IL-10 gene when induced by the glucocor... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Accuracy and potential usefulness of triplex real-time PCR for impr...
Published: June, 2008

Abstract: Bacterial identification and antibiotic susceptibility testing currently require 48 h when a first blood culture (BC) is positive for clustered gra... Read more »

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Master Mix

A link between RNA metabolism and silencing affecting Arabidopsis d...
Published: June, 2008

Abstract: MicroRNAs (miRNAs) and small interfering RNAs (siRNAs) are abundant endogenous small RNAs (smRNAs) that control transcript expression through postt... Read more »

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DNA shearing Bioruptor

Genome-wide analysis reveals MOF as a key regulator of dosage compe...
Published: May, 2008

Abstract: Dosage compensation, mediated by the MSL complex, regulates X-chromosomal gene expression in Drosophila. Here we report that the histone H4 lysine ... Read more »

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Bioruptor Chromatin Shearing

Modulation of RNA polymerase assembly dynamics in transcriptional r...
Published: May, 2008

Abstract: The interaction of transcription factors with target genes is highly dynamic. Whether the dynamic nature of these interactions is merely an intrins... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Dorsal interacting protein 3 potentiates activation by Drosophila R...
Published: May, 2008

Abstract: Dorsal interacting protein 3 (Dip3) contains a MADF DNA-binding domain and a BESS protein interaction domain. The Dip3 BESS domain was previously s... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Bmi1 regulates memory CD4 T cell survival via repression of the Nox...
Published: May, 2008

Abstract: The maintenance of memory T cells is central to the establishment of immunological memory, although molecular details of the process are poorly und... Read more »

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MeDIP kit

Highly integrated single-base resolution maps of the epigenome in A...
Published: May, 2008

Abstract: Deciphering the multiple layers of epigenetic regulation that control transcription is critical to understanding how plants develop and respond to ... Read more »

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DNA shearing Bioruptor

Dispersibility and stability improvement of unfunctionalized nanotu...
Published: May, 2008

Abstract: Improvement on the stability and loading of unfunctionalized single wall carbon nanotubes (SWNTs) in amide solvents is necessary to enhance the per... Read more »

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Bioruptor

Formation of composite organic thin film transistors with nanotubes...
Published: May, 2008

Abstract: Plastic electronics is a rapidly expanding topic, much of which has been focused on organic semiconductors. However, it is also of interest to find... Read more »

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Bioruptor

Optical trapping of carbon nanotubes
Published: May, 2008

Abstract: Optical trapping is a new tool for the manipulation and deposition of single wall carbon nanotube (SWNT) bundles. We present a study on optical tra... Read more »

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Bioruptor

Inactivation of a Human Kinetochore by Specific Targeting of Chroma...
Published: April, 2008

Abstract: We have used a human artificial chromosome (HAC) to manipulate the epigenetic state of chromatin within an active kinetochore. The HAC has a dimeri... Read more »

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DNA shearing Antibody

Cell cycle association of the retinoblastoma protein Rb and the his...
Published: April, 2008

Abstract: The Epstein-Barr virus C promoter (Cp) regulates the major multicistronic transcript encoding the EBNA-LP, 1, 2, and 3 genes required for B-cell pr... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Identification of CIITA regulated genetic module dedicated for anti...
Published: April, 2008

Abstract: The class II trans-activator CIITA is a transcriptional co-activator required for the expression of Major Histocompatibility Complex (MHC) genes. A... Read more »

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Antibody

SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric...
Published: March, 2008

Abstract: The Sir2 deacetylase regulates chromatin silencing and lifespan in Saccharomyces cerevisiae. In mice, deficiency for the Sir2 family member SIRT6 l... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Global transcription regulation by DNA topoisomerase I in exponenti...
Published: March, 2008

Abstract: To establish the cellular functions of DNA topoisomerase I-B (Top1p) at a global level, we have determined the expression profiles and histone modi... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

The Friedreich ataxia GAA repeat expansion mutation induces compara...
Published: March, 2008

Abstract: Friedreich ataxia (FRDA) is caused by a homozygous GAA repeat expansion mutation within intron 1 of the FXN gene, leading to reduced expression of ... Read more »

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Antibody

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