The 0.2 ml Bioruptor® Microtubes for DNA and chromatin shearing strongly improve DNA and chromatin sonication efficiency. These tubes have been thoroughly validated for use on the Bioruptor® Pico and are strongly recommended for DNA and chromatin shearing applications using this instrument. Recommended sample volume: 20-100 μl.
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We strongly recommend using this: 0.2 ml microtubes for Bioruptor® Pico (Hologic Diagenode Cat# C30010020). Click here to copy to clipboard.
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Targeted bisulfite sequencing for biomarker discovery. Morselli, M and Farrell, C and Rubbi, L and Fehling, HL and Henkhaus, Rand Pellegrini, M Cytosine methylation is one of the best studied epigenetic modifications. In mammals, DNA methylation patterns vary among cells and is mainly found in the CpG context. DNA methylation is involved in important processes during development and differentiation and its dysregulation can lead to or is associated with dis...
