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Exclusive Highly Specific Kits Antibodies for DNA HydroxyMethylation Studies

Cytosine hydroxymethylation was recently discovered as an important epigenetic mechanism. This cytosine base modification results from the enzymatic conversion of 5-methylcytosine (5-mC) into 5-hydroxymethylcytosine (5-hmC) by the TET family of oxygenases. Though the precise role of 5-hmC is the subject of intense research and debate, early studies strongly indicate that it is also involved in gene regulation and in numerous important biological processes including embryonic development, cellular differentiation, stem cell reprogramming and carcinogenesis.

The study of 5-hmC has long been limited due to the lack of high quality, validated tools and technologies that discriminate hydroxymethylation from methylation in regulating gene expression. The use of highly specific antibodies against 5-hmC for the immunoprecipitation of hydroxymethylated DNA offers a reliable solution for hydroxymethylation profiling.

相关产品

  • Mouse IgG
    C15200081-100
    5-methylcytosine (5-mC) Antibody - clone 33D3
  • Mouse IgG
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    5-hydroxymethylcytosine (5-hmC) monoclonal anti...
  • Mouse IgG
    C15220001-50
    5-hydroxymethylcytosine (5-hmC) monoclonal anti...
  • Mouse IgG
    C15220001-100
    5-hydroxymethylcytosine (5-hmC) monoclonal anti...
  • Mouse IgG
    C15220001-20
    5-hydroxymethylcytosine (5-hmC) monoclonal anti...
  • Mouse IgG
    C15200200-50
    5-hydroxymethylcytosine (5-hmC) monoclonal anti...
  • Mouse IgG
    C15200200-100
    5-hydroxymethylcytosine (5-hmC) monoclonal anti...
  • Mouse IgG
    C15410205-20
    5-hydroxymethylcytosine (5-hmC) polyclonal anti...
  • Mouse IgG
    C15410205-50
    5-hydroxymethylcytosine (5-hmC) polyclonal anti...
  • Methylation kit icon
    C02010031
    hMeDIP kit x16 (monoclonal mouse antibody)
  • Methylation kit icon
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    Auto hMeDIP kit x16 (monoclonal mouse antibody)

活动

  • DNA methylation workshop: Become an expert at RRBS
    Diagenode
    Oct 1-Oct 31, 2021
  • Dutch Chromatin Meeting
    Radboud UMC, Geert Grooteplein 15, 6525 EZ Nijmegen, The Netherlands, Experience center, route 292 to 307
    Nov 12, 2021
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