Diagenode

Super enhancer associated RAI14 is a new potential biomarker in lung adenocarcinoma


Chongze Yuan, Hong Hu,Muyu Kuang, Zongwei Chen,Xiaoting Tao,Shengjian Fang,Yihua Sun,Yawei Zhang, and Haiquan Chen

Tyrosine kinase inhibitors (TKIs) are widely used to treat lung adenocarcinoma patients with EGFR mutations or ALK-fusions. However, patients with wild-type genes or TKIs-resistant mutations lack effective therapeutic targets. Extensive studies reveal that super enhancer (SE), a large cis-regulatory element, is associated with key oncogenes in a variety of cancers. By comparing the effect of SE on lung adenocarcinoma cell lines with normal cell line, this work attempts to find new biomarkers and potential therapeutic targets for lung adenocarcinoma.

Tags
Bioruptor

Share this article

Published
December, 2017

Source

ニュース

 すべてのニュースを見る


The European Regional Development Fund and Wallonia are investing in your future.

Extension of industrial buildings and new laboratories.



  ABOUT SSL CERTIFICATES

       Site map   |   Contact us   |   Conditions of sales   |   Conditions of purchase   |   Privacy policy   |   Diagenode Diagnostics