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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Sumoylation at chromatin governs coordinated repression of a transc...
Published: October, 2013
Abstract: Despite numerous studies on specific sumoylated transcriptional regulators, the global role of SUMO on chromatin in relation to transcription regul... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Cell-Autonomous Regulation of Brown Fat Identity Gene UCP1 by Unlig...
Published: October, 2013
Abstract: White adipose tissue stores energy in the form of lipids, and brown adipose tissue expends energy via uncoupled fatty acid oxidation, which leads t... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Dissection of the elements of osmotic stress response transcription...
Published: October, 2013
Abstract: The response to hyperosmotic stress is mediated by the HOG pathway. The MAP kinase Hog1 activates several transcription factors, regulates chromati... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Recombinant antibodies to histone post-translational modifications.
Published: October, 2013
Abstract: Variability in the quality of antibodies to histone post-translational modifications (PTMs) is a widely recognized hindrance in epigenetics researc... Read more »
Pregnenolone activates CLIP-170 to promote microtubule growth and c...
Published: October, 2013
Abstract: Pregnenolone (P5) is a neurosteroid that improves memory and neurological recovery. It is also required for zebrafish embryonic development. Howeve... Read more »
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Bioruptor
MEF2B mutations lead to deregulated expression of the oncogene BCL6...
Published: October, 2013
Abstract: MEF2B encodes a transcriptional activator and is mutated in ∼11% of diffuse large B cell lymphomas (DLBCLs) and ∼12% of follicular lymphomas (FLs).... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Oxidative bisulfite sequencing of 5-methylcytosine and 5-hydroxymet...
Published: October, 2013
Abstract: To uncover the function of and interplay between the mammalian cytosine modifications 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC), ne... Read more »
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DNA shearing Bioruptor
The trithorax group proteins Kismet and ASH1 promote H3K36 dimethyl...
Published: October, 2013
Abstract: Members of the Polycomb group of repressors and trithorax group of activators maintain heritable states of transcription by modifying nucleosomal h... Read more »
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Antibody
Early histone modifications in the ventromedial hypothalamus and pr...
Published: October, 2013
Abstract: Expression of the primary female sex behaviour, lordosis, in laboratory animals depends on oestrogen-induced expression of progesterone receptor (P... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Epigenetic memory at embryonic enhancers identified in DNA methylat...
Published: October, 2013
Abstract: Mammalian development requires cytosine methylation, a heritable epigenetic mark of cellular memory believed to maintain a cell's unique gene expre... Read more »
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DNA shearing Bioruptor
DNA methylation analysis of murine hematopoietic side population ce...
Published: October, 2013
Abstract: Stem cells have been found in most tissues/organs. These somatic stem cells produce replacements for lost and damaged cells, and it is not complete... Read more »
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IP-Star
Genome-wide shRNA screening to identify factors mediating Gata6 rep...
Published: October, 2013
Abstract: The use of whole-genome pooled shRNA libraries in loss-of-function screening in tissue culture models provides an effective means to identify novel... Read more »
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Antibody
Sequestration by IFIT1 impairs translation of 2'O-unmethylated capp...
Published: October, 2013
Abstract: Viruses that generate capped RNA lacking 2'O methylation on the first ribose are severely affected by the antiviral activity of Type I interferons.... Read more »
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Bioruptor Cell Lysis Mass Spectrometry
Identification of FOXM1-induced epigenetic markers for head and nec...
Published: October, 2013
Abstract: BACKGROUND Epigenetic reprogramming of the methylome has been implicated in all stages of cancer evolution. It is now well accepted that cancer ce... Read more »
Dynamic changes in DNA methylation and hydroxymethylation when hES ...
Published: October, 2013
Abstract: DNA methylation and hydroxymethylation have been implicated in normal development and differentiation, but our knowledge is limited about the genom... Read more »
Transcription termination and chimeric RNA formation controlled by ...
Published: October, 2013
Abstract: Alternative cleavage and polyadenylation influence the coding and regulatory potential of mRNAs and where transcription termination occurs. Althoug... Read more »
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Antibody
tRNA methyltransferase homolog gene TRMT10A mutation in young onset...
Published: October, 2013
Abstract: We describe a new syndrome of young onset diabetes, short stature and microcephaly with intellectual disability in a large consanguineous family wi... Read more »
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Bioruptor Tissue Homogenization
Lamin A/C-promoter interactions specify chromatin state-dependent t...
Published: October, 2013
Abstract: The nuclear lamina is implicated in the organization of the eukaryotic nucleus. Association of nuclear lamins with the genome occurs through large ... Read more »
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Bioruptor Chromatin Shearing Antibody
Cap Completion and C-Terminal Repeat Domain Kinase Recruitment Unde...
Published: October, 2013
Abstract: After transcription initiation, RNA polymerase (Pol) II escapes from the promoter and recruits elongation factors. The molecular basis for the init... Read more »
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Bioruptor Chromatin Shearing
Genome-wide profiling reveals stimulus-specific functions of p53 du...
Published: September, 2013
Abstract: How tumor suppressor p53 selectively responds to specific signals, especially in normal cells, is poorly understood. We performed genome-wide profi... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Tissue-specific differences in the regulation of KIBRA gene express...
Published: September, 2013
Abstract: KIBRA has been described as a key regulator of the Hippo signaling pathway, regulating organ size control, cell contact inhibition, cell growth, as... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Gene regulation and priming by topoisomerase IIα in embryonic stem ...
Published: September, 2013
Abstract: Topoisomerases resolve torsional stress, while their function in gene regulation, especially during cellular differentiation, remains unknown. Here... Read more »
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Bioruptor Chromatin Shearing ChIP-seq Bioruptor Plus
TET2 is a Master Regulator of Smooth Muscle Cell Plasticity
Published: September, 2013
Abstract: Background—Smooth muscle cells (SMC) are remarkably plastic. Their reversible differentiation is required for growth and wound healing, but also co... Read more »
Human SNP Links Differential Outcomes in Inflammatory and Infectiou...
Published: September, 2013
Abstract: The clinical course and eventual outcome, or prognosis, of complex diseases varies enormously between affected individuals. This variability critic... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Hira-dependent histone H3.3 deposition facilitates PRC2 recruitment...
Published: September, 2013
Abstract: Polycomb repressive complex 2 (PRC2) regulates gene expression during lineage specification through trimethylation of lysine 27 on histone H3 (H3K2... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Addiction of t(8;21) and inv(16) acute myeloid leukemia to native R...
Published: September, 2013
Abstract: The t(8;21) and inv(16) chromosomal aberrations generate the oncoproteins AML1-ETO (A-E) and CBFβ-SMMHC (C-S). The role of these oncoproteins in ac... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Insulin-activated Elk-1 recruits the TIP60/NuA4 complex to increase...
Published: September, 2013
Abstract: Insulin increases prolactin gene expression in GH4 cells through phosphorylation of Elk-1 (Jacob and Stanley, 2001). We preformed a reverse two-hyb... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Dnmt3L antagonizes DNA methylation at bivalent promoters and favors...
Published: September, 2013
Abstract: The de novo DNA methyltransferase 3-like (Dnmt3L) is a catalytically inactive DNA methyltransferase that cooperates with Dnmt3a and Dnmt3b to methy... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Identification of an Enhancer That Increases miR-200b~200a~429 Gene...
Published: September, 2013
Abstract: The miR-200b~200a~429 gene cluster is a key regulator of EMT and cancer metastasis, however the transcription-based mechanisms controlling its expr... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
The Reelin receptors ApoER2 and VLDLR are direct target genes of HI...
Published: September, 2013
Abstract: The tumor suppressor gene HIC1 (Hypermethylated In Cancer 1) is located in 17p13.3 a region frequently hypermethylated or deleted in tumors and in ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR

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