Publications,References

Targeted disruption of hotair leads to homeotic transformation and ...
Published: October, 2013

Abstract: Long noncoding RNAs (lncRNAs) are thought to be prevalent regulators of gene expression, but the consequences of lncRNA inactivation in vivo are mo... Read more »

Tags
Antibody H3K27me3 (C15410069)

IL-4 blocks TH1-polarizing/inflammatory cytokine gene expression du...
Published: October, 2013

Abstract: BACKGROUND: Whereas recent research has characterized the mechanism by which dendritic cells (DCs) induce TH1/TH17 responses, the functional specia... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

Gene dysregulation by histone variant H2A.Z in bladder cancer
Published: October, 2013

Abstract: Background The incorporation of histone variants into nucleosomes is one of the main strategies that the cell uses to regulate the structure and ... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-seq

The SERRATE protein is involved in alternative splicing in Arabidop...
Published: October, 2013

Abstract: How alternative splicing (AS) is regulated in plants has not yet been elucidated. Previously, we have shown that the nuclear cap-binding protein co... Read more »

Tags
Bioruptor Cell Lysis Bioruptor Plus

Gene regulatory scenarios of primary 1,25-dihydroxyvitamin d3 targe...
Published: October, 2013

Abstract: Genome- and transcriptome-wide data has significantly increased the amount of available information about primary 1,25-dihydroxyvitamin D3 (1,25(OH... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus

Dimethyl fumarate regulates histone deacetylase expression in astro...
Published: October, 2013

Abstract: We previously showed that dimethyl fumarate (DMF) reduces inflammatory activation in astrocytes, involving activation of transcription factor Nrf2.... Read more »

Tags
Antibody

Evidence of population bottleneck in Astragalus michauxii (Fabaceae...
Published: October, 2013

Abstract: Genetic factors such as decreased genetic diversity and increased homozygosity can have detrimental effects on rare species, and may ultimately lim... Read more »

Tags
DNA shearing Bioruptor

Blimp1 (Prdm1) prevents re-specification of photoreceptors into ret...
Published: October, 2013

Abstract: During retinal development, photoreceptors and bipolar cells express the transcription factor Otx2. Blimp1 is transiently expressed in Otx2+ cells.... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

Lack of decorin expression by human bladder cancer cells offers new...
Published: October, 2013

Abstract: Decorin, a multifunctional small leucine-rich extracellular matrix proteoglycan, has been shown to possess potent antitumour activity. However, the... Read more »

Tags
IP-Star

CTCF binding site sequence differences are associated with unique r...
Published: October, 2013

Abstract: CTCF (CCCTC-binding factor) is a highly conserved multifunctional DNA-binding protein with thousands of binding sites genome-wide. Our previous wor... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-seq

Global analysis of eukaryotic mRNA degradation reveals Xrn1-depende...
Published: October, 2013

Abstract: The rates of mRNA synthesis and degradation determine cellular mRNA levels and can be monitored by comparative dynamic transcriptome analysis (cDTA... Read more »

Tags
Bioruptor

Global DNA methylation screening of liver in piperonyl butoxide-tre...
Published: October, 2013

Abstract: Disruptive epigenetic gene control has been shown to be involved in carcinogenesis. To identify key molecules in piperonyl butoxide (PBO)-induced h... Read more »

Tags
DNA shearing Antibody MeDIP kit 5mC (C15200081)

NLRP7 affects trophoblast lineage differentiation, binds to overexp...
Published: October, 2013

Abstract: Maternal-effect mutations in NLRP7 cause rare biparentally inherited hydatidiform moles (BiHMs), abnormal pregnancies containing hypertrophic vesic... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

Sox2 Expression Is Regulated by a Negative Feedback Loop in Embryon...
Published: October, 2013

Abstract: The self-renewal and pluripotency of embryonic stem cells (ESC) is regulated by a highly integrated network of essential transcription factors, whi... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

Combined modulation of polycomb and trithorax genes rejuvenates β c...
Published: October, 2013

Abstract: Inadequate functional β cell mass underlies both type 1 and type 2 diabetes. β Cell growth and regeneration also decrease with age through mechanis... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR Antibody

Spt6 regulates intragenic and antisense transcription, nucleosome p...
Published: October, 2013

Abstract: Spt6 is a highly conserved histone chaperone that interacts directly with both RNA polymerase II and histones to regulate gene expression. To gain ... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-seq

Membrane-to-nucleus signaling links insulin-like growth factor-1- a...
Published: October, 2013

Abstract: STEM CELL FACTOR (MOUSE: Kitl, human: KITLG) and insulin-like growth factor-1 (IGF1), acting via KIT and IGF1 receptor (IGF1R), respectively, are c... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

A Conserved Protein Motif Is Required for Full Modulatory Activity ...
Published: October, 2013

Abstract: NELF-B is a BRCA1-interacting protein and subunit (with NELF-A, -C/D, and -E) of the human negative elongation factor (NELF) complex, which partici... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

Angiomodulin is required for cardiogenesis of embryonic stem cells ...
Published: October, 2013

Abstract: The transcription factor p63, member of the p53 gene family, encodes for two main isoforms, TAp63 and ΔNp63 with distinct functions on epithelial h... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-seq

Class I Lysine Deacetylases Facilitate Glucocorticoid-induced Trans...
Published: October, 2013

Abstract: Nuclear receptors use lysine acetyltransferases and lysine deacetylases (KDACs) in regulating transcription through histone acetylation. Lysine ace... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

Transcriptional induction of ADAMTS5 protein by nuclear factor-κB (...
Published: October, 2013

Abstract: Here we sought to identify transcription factors that induce ADAMTS5, a crucial proteinase for osteoarthritis development. Exhaustive comparison of... Read more »

PRMT5-mediated histone H4 arginine-3 symmetrical dimethylation mark...
Published: October, 2013

Abstract: Symmetrical dimethylation on arginine-3 of histone H4 (H4R3me2s) has been reported to occur at several repressed genes, but its specific regulation... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-seq

Epstein-Barr virus-mediated transformation of B cells induces globa...
Published: October, 2013

Abstract: Epstein-Barr virus (EBV) infects and transforms human primary B cells inducing indefinite proliferation. To investigate the potential participation... Read more »

Tags
Antibody

Genomic organization of human transcription initiation complexes.
Published: October, 2013

Abstract: The human genome is pervasively transcribed, yet only a small fraction is coding. Here we address whether this non-coding transcription arises at p... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-seq

A three-component signaling system finetunes expression kinetics of...
Published: October, 2013

Abstract: During adaptation to environments, bacteria employ two-component signal transduction systems, which contain histidine kinases and response regulato... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus

ErbB2 upregulates the Na+,HCO3--cotransporter NBCn1/SLC4A7 in human...
Published: October, 2013

Abstract: Misregulation of acid-base transport plays central roles in cancer development. We previously demonstrated the strong up-regulation of the Na(+),HC... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus

Whole-exome sequencing supports genetic heterogeneity in childhood ...
Published: October, 2013

Abstract: The genetic basis of complex neurological disorders involving language are poorly understood, partly due to the multiple additive genetic risk fact... Read more »

Tags
DNA shearing Bioruptor

DNMT1 Is Regulated by ATP-Citrate Lyase and Maintains Methylation P...
Published: October, 2013

Abstract: During adipocyte differentiation, significant epigenomic changes occur in association with the implementation of the adipogenic program. We have pr... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus

FSHD muscular dystrophy region gene 1 binds Suv4-20h1 histone methy...
Published: October, 2013

Abstract: Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal dominant myopathy with a strong epigenetic component. It is associated with deletion ... Read more »

Tags
Antibody

The APSES transcription factor Efg1 is a global regulator that cont...
Published: October, 2013

Abstract: Efg1 (a member of the APSES family) is an important regulator of hyphal growth and of the white-to-opaque transition in Candida albicans and very c... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-seq

Publications

Events

News