Publications,References

Langerhans cells are generated by two distinct PU.1-dependent trans...
Published: December, 2013

Abstract: Langerhans cells (LCs) are the unique dendritic cells found in the epidermis. While a great deal of attention has focused on defining the developme... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

UTX coordinates steroid hormone-mediated autophagy and cell death.
Published: December, 2013

Abstract: Correct spatial and temporal induction of numerous cell type-specific genes during development requires regulated removal of the repressive histone... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Local depletion of DNA methylation identifies a repressive p53 regu...
Published: December, 2013

Abstract: Genome-scale mapping suggests that the function of DNA methylation varies with genomic context beyond transcriptional repression. However, the use ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

NCoR controls glioblastoma tumor cell characteristics.
Published: December, 2013

Abstract: BACKGROUND: We have previously shown that the transcriptional coregulator NCoR represses astrocytic differentiation of neural stem cells, suggestin... Read more »

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HighCell ChIP kit

miR-16 and miR-26a target checkpoint kinases Wee1 and Chk1 in respo...
Published: December, 2013

Abstract: The tumour suppressor p53 is a crucial regulator of cell cycle arrest and apoptosis by acting as a transcription factor to regulate a variety of ge... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

p53 status determines the role of autophagy in pancreatic tumour de...
Published: December, 2013

Abstract: Macroautophagy (hereafter referred to as autophagy) is a process in which organelles termed autophagosomes deliver cytoplasmic constituents to lyso... Read more »

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Bioruptor

HDAC inhibitor confers radiosensitivity to prostate stem-like cells.
Published: December, 2013

Abstract: Background:Radiotherapy can be an effective treatment for prostate cancer, but radiorecurrent tumours do develop. Considering prostate cancer heter... Read more »

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Antibody

β-Globin cis-elements determine differential nuclear targeting thro...
Published: December, 2013

Abstract: Increasing evidence points to nuclear compartmentalization as a contributing mechanism for gene regulation, yet mechanisms for compartmentalization... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

The maize glossy13 gene, cloned via BSR-Seq and Seq-walking encodes...
Published: December, 2013

Abstract: Aerial plant surfaces are covered by epicuticular waxes that among other purposes serve to control water loss. Maize glossy mutants originally iden... Read more »

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DNA shearing Bioruptor

Oncogenic K-Ras and loss of Smad4 mediate invasion by activating an...
Published: December, 2013

Abstract: Activating K-Ras mutations and inactivating mutations of Smad4 are two common genetic alterations that occur in the development and progression of ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Reprogramming of lysosomal gene expression by interleukin-4 and Stat6
Published: December, 2013

Abstract: Background Lysosomes play important roles in multiple aspects of physiology, but the problem of how the transcription of lysosomal genes is coord... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Master Mix

The role of Ctk1 kinase in termination of small non-coding RNAs.
Published: December, 2013

Abstract: Transcription termination in Saccharomyces cerevisiae can be performed by at least two distinct pathways and is influenced by the phosphorylation s... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Transcriptional activation of Mina by Sp1/3 factors.
Published: December, 2013

Abstract: Mina is an epigenetic gene regulatory protein known to function in multiple physiological and pathological contexts, including pulmonary inflammati... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

The Emerging Role of SOX2 in Cell Proliferation and Survival and It...
Published: December, 2013

Abstract: Tumor cells have long been observed to share several biological characteristics with normal stem/progenitor cells; however, the oncogenic mechanism... Read more »

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LowCell ChIP kit

ZRF1 controls the retinoic acid pathway and regulates leukemogenic ...
Published: December, 2013

Abstract: Acute myeloid leukemia (AML) is frequently linked to epigenetic abnormalities and deregulation of gene transcription, which lead to aberrant cell p... Read more »

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Bioruptor Cell Lysis Antibody

Distinctive patterns of epigenetic marks are associated with promot...
Published: December, 2013

Abstract: BACKGROUND: The long terminal repeat (LTR) retrotransposons and the non-LTR retrotransposons (LINE-1 or L1) make up more than one-third of the mous... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Elevated levels of FOXA1 facilitate androgen receptor chromatin bin...
Published: December, 2013

Abstract: Castration-resistant prostate cancer (CRPC) continues to pose a significant clinical challenge with new generation second-line hormonal therapies a... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Transcription factor occupancy can mediate active turnover of DNA m...
Published: December, 2013

Abstract: Distal regulatory elements, including enhancers, play a critical role in regulating gene activity. Transcription factor binding to these elements c... Read more »

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DNA shearing Bioruptor

The PAF complex and Prf1/Rtf1 delineate distinct Cdk9-dependent pat...
Published: December, 2013

Abstract: Cyclin-dependent kinase 9 (Cdk9) promotes elongation by RNA polymerase II (RNAPII), mRNA processing, and co-transcriptional histone modification. C... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Genome-wide analysis of DNA methylation changes induced by gestatio...
Published: December, 2013

Abstract: Inorganic arsenic is known to be a human carcinogen. Previous studies have reported that DNA methylation changes are involved in arsenic-induced ca... Read more »

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Antibody

Rapid Transposon Liquid Enrichment Sequencing (TnLE-seq) for Gene F...
Published: December, 2013

Abstract: Whole-genome fitness analysis in microbes that uses saturating transposon mutagenesis combined with massively parallel sequencing (Tn-seq) is provi... Read more »

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DNA shearing Bioruptor

Alternative End-Joining and Classical Nonhomologous End-Joining Pat...
Published: December, 2013

Abstract: Classical nonhomologous end-joining (C-NHEJ) and alternative end-joining (A-EJ) are the main DNA double-strand break (DSB) repair pathways when a s... Read more »

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DNA shearing Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus

Hitchhiker antigens: Inconsistent ChIP results, questionable immuno...
Published: December, 2013

Abstract: Questionable data and poor antibody performance may have a common factor: antigens "hitchhiking" on the very antibodies designed to target them. He... Read more »

A key role for EZH2 in epigenetic silencing of HOX genes in mantle ...
Published: December, 2013

Abstract: The chromatin modifier EZH2 is overexpressed and associated with inferior outcome in mantle cell lymphoma (MCL). Recently, we demonstrated preferen... Read more »

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Antibody H3K27me3 (C15410069)

The T antigen locus of merkel cell polyomavirus downregulates human...
Published: December, 2013

Abstract: Establishment of a chronic infection is a key event in virus-mediated carcinogenesis. Several cancer-associated, double-stranded DNA (dsDNA) viruse... Read more »

Two Histone Deacetylases, FfHda1 and FfHda2, Are Important for Fusa...
Published: December, 2013

Abstract: Histone modifications are crucial for the regulation of secondary metabolism in various filamentous fungi. Here we studied the involvement of histo... Read more »

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Bioruptor Bioruptor Plus

Reduced C9orf72 gene expression in c9FTD/ALS is caused by histone t...
Published: December, 2013

Abstract: Individuals carrying (GGGGCC) expanded repeats in the C9orf72 gene represent a significant portion of patients suffering from amyotrophic lateral s... Read more »

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Antibody

Genome-wide chromatin analysis in mature mouse and human spermatozoa.
Published: December, 2013

Abstract: At the end of mammalian spermatogenesis, chromatin in differentiating germ cells is extensively remodeled, with the majority of nucleosomes being r... Read more »

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Bioruptor Bioruptor Plus

The microRNA miR-433 promotes renal fibrosis by amplifying the TGF-...
Published: December, 2013

Abstract: The TGF-β/Smad3 pathway plays a major role in tissue fibrosis, but the precise mechanisms are not fully understood. Here we identified microRNA miR... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Mediator links transcription and DNA repair by facilitating Rad2/XP...
Published: December, 2013

Abstract: Mediator is a large multiprotein complex conserved in all eukaryotes. The crucial function of Mediator in transcription is now largely established.... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

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