Diagenode

Recombinant Histone H3.3-H4 tetramers

default alt
Catalog Number
Format
Price
C23010014
50 µg
$340.00

Tetramer of 2 full length N-terminal Flag tagged recombinant histone H4 units and 2 N-terminal His tagged recombinant histone H3.3 units, produced in E. coli.

  • Protein description

    Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Two core histones of each class H2A, H2B, H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric nucleosome. Histone tails undergo numerous post-translational modifications, which either directly or indirectly alter chromatin structure to facilitate transcriptional activation or repression or other nuclear processes. The histone variant H3.3 replaces conventional H3.1 in a wide range of nucleosomes in active genes. H3.3 constitutes the predominant form of histone H3 in non-dividing cells.

  • Quality control

    Figure 1.
    SDS page of the Recombinant Histone H3.3-H4 tetramers. The position of the protein of interest is indicated on the right; the marker (in kDa) is shown on the left.

    Figure 2.
    ESi-TOF analysis of the Recombinant Histone H3.3-H4 tetramers.

  • Documents
    C23010014 histone H3-3 DATASHEET
    C23010014 histone H3-3 tds
    Download
  • Publications

    How to properly cite this product in your work

    Diagenode strongly recommends using this: Recombinant Histone H3.3-H4 tetramers (Diagenode Cat# C23010014). Click here to copy to clipboard.

    Using our products in your publication? Let us know!

  • Related products

Events

  • Workshop on Chromatin Proteomics
    Crete, Greece
    Oct 3-Oct 8, 2016
  • 2nd Annual Next Generation Sequencing Congress
    Boston, USA
    Oct 3-Oct 4, 2016
  • XXXIX Reunión anual de la Sociedad de Bioquimica y Biología Molecular de Chile
    Puerto Varas, Chile
    Sep 27-Sep 30, 2016
 See all events

Twitter feed

News

 See all news