Ubiquitin recombinant protein - biotinylated
Covalent binding of ubiquitin to other proteins is one of the most frequent posttranslational modifiations. This covalent attachment can be either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Conjugation of ubiquitin to its target protein can lead to various effects within a cell, including protein degradation, DNA repair, cell cycle regulation, kinase modification, endocytosis, and regulation of other cell signaling pathways.
Purified using FPLC, >98% purity as determined by SDS-PAGE.
20mM Tris-Cl pH 7.6, 1 mM EDTA, 0.15 M NaCl, 10% glycerol, 0.5 mM PMSF and 1 mM DTT.
Store at-80°C; guaranteed stable for 2 years from date of receipt when stored properly.
Precautions: This product is for research use only. Not for use in diagnostic or therapeutic procedures.