Diagenode

Human Recombinant Nucleosome

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Catalog Number
Format
Price
C01030101
5 µg
$425.00

Recombinant nucleosome, assembled in vitro by salt dialysis using the 147 bp 601 DNA sequence and the four core histones, H2A, H2B, H3 and H4, produced in E. Coli.

  • Protein description

    The nucleosome is the smallest part of the chromosome. It consists of two core histones of each class H2A, H2B, H3 and H4 which assemble and are wrapped around 146 base pairs of DNA. Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They pack the DNA into tight masses of chromatin. Histones are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histone tails undergo numerous post-translational modifications, which either directly or indirectly alter chromatin structure to facilitate transcriptional activation or repression or other nuclear processes.

     

     

  • Quality control

    Figure 1.
    Native page of the human recombinant nucleosome (lane 2). Lane 1 shows the 147 bp 601 DNA sequence.

  •  資料
    C01030101 human recombinant nucleosome DATASHEET
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  •  出版物

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イベント

  • IMB Conference on "Epigenetics of Ageing - Responses to Adversity across Scales" 2022
    Rheinland-Pfalz, Germany
    Jun 28-Jul 1, 2022
  • CNET 2022
    Gif-Sur-Yvette, France
    Jul 4-Jul 6, 2022
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