Diagenode

HighCell# ChIP kit protein A

カタログ番号
フォーマット
価格
C01010062
(kch-mahigh-A48)
48 rxns
$1,280.00
ブローカー情報

The Diagenode HighCell# ChIP kit protein A contains protein A-coated paramagnetic beads and negative IgG from rabbit. This kit is recommended to perform ChIP with rabbit polyclonal and monoclonal antibodies.

Perform ChIP with up to 10 million cells per IP. Recover more DNA and limit bias downstream applications.

  • 特徴
    • Use from 1,000,000 - 10,000,000 cells per IP
    • Recover large amounts of DNA
    • Ideal for ChIP of low abundant proteins
    • Improved handling and reproducibility due to magnetic beads and a uniquely designed magnetic rack (DiaMag1.5)
  •  資料
    HighCell# ChIP kit MANUAL
    The Diagenode HighCell# ChIP kit protein A contains protein A-coated paramagnetic beads (...
    Download
    Chromatin Immunoprecipitation Brochure BROCHURE
    Whether you are experienced or new to the field of chromatin immunoprecipitation, Diagenode has e...
    Download
  •  出版物

    How to properly cite this product in your work

    Diagenode strongly recommends using this: HighCell# ChIP kit protein A (Diagenode Cat# C01010062). Click here to copy to clipboard.

    Using our products in your publication? Let us know!

    UCP1 transrepression in Brown Fat in vivo and mineralocorticoid receptor anti-thermogenic effects.
    Kuhn E, Lamribet K, Viengchareun S, Le Menuet D, Fève B, Lombès M
    OBJECTIVES: The mineralocorticoid receptor (MR), a hormone-activated transcription factor, besides its role in controlling hydroelectrolytic homeostasis, exerts pro-adipogenic and anti-thermogenic effects, inhibiting mitochondrial-uncoupling protein UCP1 expression in brown adipocytes. The aim of this study was to g...

    HIV-2/SIV viral protein X counteracts HUSH repressor complex.
    Ghina Chougui, Soundasse Munir-Matloob, Roy Matkovic, Michaël M Martin, Marina Morel, Hichem Lahouassa, Marjorie Leduc, Bertha Cecilia Ramirez, Lucie Etienne   and Florence Margottin-Goguet
    To evade host immune defences, human immunodeficiency viruses 1 and 2 (HIV-1 and HIV-2) have evolved auxiliary proteins that target cell restriction factors. Viral protein X (Vpx) from the HIV-2/SIVsmm lineage enhances viral infection by antagonizing SAMHD1 (refs ), but this antagonism is not sufficient to explain a...

    NFE2-Related Transcription Factor 2 Coordinates Antioxidant Defense with Thyroglobulin Production and Iodination in the Thyroid Gland.
    Ziros PG, Habeos IG, Chartoumpekis DV, Ntalampyra E, Somm E, Renaud CO, Bongiovanni M, Trougakos IP, Yamamoto M, Kensler TW, Santisteban P, Carrasco N, Ris-Stalpers C, Amendola E, Liao XH, Rossich L, Thomasz L, Juvenal GJ, Refetoff S, Sykiotis GP
    BACKGROUND: The thyroid gland has a special relationship with oxidative stress. While generation of oxidative substances is part of normal iodide metabolism during thyroid hormone synthesis, the gland must also defend itself against excessive oxidation in order to maintain normal function. Antioxidant and detoxifica...

    T Cell Receptor-Regulated TGF-β Type I Receptor Expression Determines T Cell Quiescence and Activation.
    Tu E, Chia CPZ, Chen W, Zhang D, Park SA, Jin W, Wang D, Alegre ML, Zhang YE, Sun L, Chen W
    It is unclear how quiescence is enforced in naive T cells, but activation by foreign antigens and self-antigens is allowed, despite the presence of inhibitory signals. We showed that active transforming growth factor β (TGF-β) signaling was present in naive T cells, and T cell receptor (TCR)...

    HDAC1 and HDAC2 Modulate TGF-β Signaling during Endothelial-to-Hematopoietic Transition.
    Thambyrajah R, Fadlullah MZH, Proffitt M, Patel R, Cowley SM, Kouskoff V, Lacaud G
    The first hematopoietic stem and progenitor cells are generated during development from hemogenic endothelium (HE) through trans-differentiation. The molecular mechanisms underlying this endothelial-to-hematopoietic transition (EHT) remain poorly understood. Here, we explored the role of the epigenetic regulators HD...

    RNA-binding protein HuR enhances mineralocorticoid signaling in renal KC3AC1 cells under hypotonicity
    Lema I. et al.
    Mineralocorticoid receptor (MR) mediates the sodium-retaining action of aldosterone in the distal nephron. Herein, we decipher mechanisms by which hypotonicity increases MR expression in renal principal cells. We identify HuR (human antigen R), an mRNA-stabilizing protein, as an important posttranscriptional re...

    Stem cell-like transcriptional reprogramming mediates metastatic
    Mateo F. et al.
    Inhibitors of the mechanistic target of rapamycin (mTOR) are currently used to treat advanced metastatic breast cancer. However, whether an aggressive phenotype is sustained through adaptation or resistance to mTOR inhibition remains unknown. Here, complementary studies in human tumors, cancer models and cell lines ...

    Cistrome of the aldosterone-activated mineralocorticoid receptor in human renal cells
    Le Billan F. et al.
    Aldosterone exerts its effects mainly by activating the mineralocorticoid receptor (MR), a transcription factor that regulates gene expression through complex and dynamic interactions with coregulators and transcriptional machinery, leading to fine-tuned control of vectorial ionic transport in the distal nephron. To...

    The Integrase Cofactor LEDGF/p75 Associates with Iws1 and Spt6 for Postintegration Silencing of HIV-1 Gene Expression in Latently Infected Cells.
    Gérard A, Ségéral E, Naughtin M, Abdouni A, Charmeteau B, Cheynier R, Rain JC, Emiliani S
    The persistence of a latent reservoir containing transcriptionally silent, but replication-competent, integrated provirus is a serious challenge to HIV eradication. HIV integration is under the control of LEDGF/p75, the cellular cofactor of viral integrase. Investigating possible postintegration roles for LEDGF/p75,...

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