Diagenode

SirT1 monoclonal antibody - Pioneer

RFX5-polyclonal-antibody-diagenode
Catalog Number
Format
Price
C15200063
(MAb-063-050)
50 µg/72 µl
$200.00
  Bulk order

Alternative names: SIR2, SIR2alpha, SIR2L1

Monoclonal antibody raised in mouse against human SirT1 (NAD-dependent deacetylase sirtuin-1) using a synthetic peptide.

Lot001
Concentration0.7 µg/µl
Species reactivityHuman
TypeMonoclonal
PurityProtein G purified
HostMouse
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Applications Suggested dilution References
Western Blotting 1:500 Fig 1
  • Validation Data

    Western blot

    Figure 1. Western blot analysis using the Diagenode monoclonal antibody directed against hSirT1
    Western blot was performed using nuclear extracts from HeLa cells (HeLa NE, 20 μg) and the Diagenode monoclonal antibody against hSirT1 (cat# MAb-063-050) diluted 1:500 in TBS-Tween containing 5% skimmed milk. The molecular weight marker (in kDa) is shown on the left), the position of the protein of interest is shown on the right.

  •  Applications
    WB
    Western blot : The quality of antibodies used in this technique is crucial for correct and specific protein identification. Diagenode offers huge selection of highly sensitive and specific western blot-validated antibodies. Learn more about: Load... Read more
  •  Documents
    Datasheet hSirT1 MAb-063-050 DATASHEET
    Datasheet description
    Download
  •  Publications

    How to properly cite this product in your work

    Diagenode strongly recommends using this: SirT1 monoclonal antibody - Pioneer (Diagenode Cat# C15200063 Lot# 001). Click here to copy to clipboard.

    Using our products in your publication? Let us know!

    SIRT1-dependent epigenetic regulation of H3 and H4 histone acetylation in human breast cancer
    Khaldoun Rifaï et al.
    Breast cancer is the most frequently diagnosed malignancy in women worldwide. It is well established that the complexity of carcinogenesis involves profound epigenetic deregulations that contribute to the tumorigenesis process. Deregulated H3 and H4 acetylated histone marks are amongst those alterations. Sirtuin-1 (...

    Dual SIRT1 expression patterns strongly suggests its bivalent role in human breast cancer
    Rifai K. et al.
    Breast cancer is the most common cancer in women, and the leading cause of cancer death in women worldwide. SIRT1 (silent mating type information regulation 2 homolog) 1 is a class-III histone deacetylase involved in apoptosis regulation, DNA repair and tumorigenesis. However, its role in breast carcinoma remains co...

    Hormetic Shifting of Redox Environment by Pro-Oxidative Resveratrol Protects Cells Against Stress
    Plauth A et al.
    Resveratrol has gained tremendous interest owing to multiple reported health-beneficial effects. However, the underlying key mechanism of action of resveratrol remained largely controversial. Here, we demonstrate that under physiologically relevant conditions major biological effects of resveratrol can be attributed...

  •  Related products

Events

 See all events

Applications

 See all applications



The European Regional Development Fund and Wallonia are investing in your future.

Extension of industrial buildings and new laboratories.



  ABOUT SSL CERTIFICATES

         Site map   |   Contact us   |   Conditions of sales   |   Conditions of purchase   |   Privacy policy   |   Diagenode Diagnostics