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Recombinant human Hp1 alpha (CBX5)

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Catalog Number
25 µg

Full length recombinant human N-terminal His tagged HP1a (Heterochromatin Protein 1 Homolog Alpha) protein, produced in E. coli.

  • Product Description

    HP1a recombinant protein  

    Other names

    CBX5, MOD1, M31, P25b

    Target description

    HP1 alpha (UniProt/Swiss-Prot entry P45973) is a component of heterochromatin. It recognizes and binds to histone H3 tails methylated at 'Lys-9', leading to epigenetic repression of transcription. HP1 alpha may also interact with lamin B receptor (LBR), thereby contributing to the association of the heterochromatin with the inner nuclear membrane. Further, HP1 alpha is involved in the formation of a functional kinetochore through interaction with MIS12 complex proteins.






    Purified using FPLC, >98% purity as determined by SDS-PAGE.

    Storage Buffer

    20mM Tris-Cl pH 7.6, 1 mM EDTA, 0.15 M NaCl, 10% glycerol, 0.5 mM PMSF and 1 mM DTT.


    Store at-80°C; guaranteed stable for 2 years from date of receipt when stored properly.

    Precautions: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

  • Quality Control

    Figure 1.
    SDS page of the HP1α recombinant protein. The position of the protein of interest is indicated on the right; the marker (in kDa) is shown on the left.

  •  Documents
    Recombinant human Hp1 alpha (CBX5) DATASHEET
    Full length recombinant human N-terminal His tagged HP1a (Heterochromatin Protein 1 Homolog Alpha...
  •  Publications

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