ASF1b recombinant protein
CIA-II, HAsf1b, HCIA-II
ASF1b (UniProt/Swiss-Prot entry Q9NVP2) belongs to the family of histone chaperones and interacts with both histones H3 and H4. It’s a key component for nucleosome assembly and disassembly. ASF1b cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly, but is not involved in replication-independent chromatin assembly. ASF1b is essential for spermatogenesis.
Purified using FPLC, >95% purity as determined by SDS-PAGE.
20mM Tris-Cl pH 7.6, 1 mM EDTA, 0.15 M NaCl, 10% glycerol, 0.5 mM PMSF and 1 mM DTT.
Store at-80°C; guaranteed stable for 2 years from date of receipt when stored properly.
Precautions: This product is for research use only. Not for use in diagnostic or therapeutic procedures.