Recombinant Histone H2A.Z-H2B dimers

Catalog Number
50 µg

Dimer of full length N-terminal Flag tagged recombinant histone H2A.Z and N-terminal His tagged recombinant histone H2B, produced in E. coli.

  • Protein description

    Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Two core histones of each class H2A, H2B, H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric nucleosome. Histone tails undergo numerous post-translational modifications, which either directly or indirectly alter chromatin structure to facilitate transcriptional activation or repression or other nuclear processes. The histone variant H2A.Z replaces conventional H2A in a subset of nucleosomes. H2A.Z is involved in transcriptional regulation, antisilencing, silencing, and genome stability. It functions as a key regulator of chromatin function and plays an essential role during mammalian development.

  • Quality control

    Figure 1.
    SDS page of the Recombinant Histone H2A.Z-H2B dimers. The position of the proteins of interest is indicated on the right; the marker (in kDa) is shown on the left.

    Figure 2.
    ESi-TOF analysis of the Recombinant Histone H2A.Z-H2B dimers.

  •  Documents
    C23010012 histone H2AZ-H2B DATASHEET
    C23010012 histone H2AZ-H2B tds
  •  Publications

    How to properly cite this product in your work

    Diagenode strongly recommends using this: Recombinant Histone H2A.Z-H2B dimers (Diagenode Cat# C23010012). Click here to copy to clipboard.

    Using our products in your publication? Let us know!

  •  Related products


  • ASHG
    Houston, TX
    Oct 15-Oct 19, 2019
  • ddd
    Oct 18-Oct 26, 2019
  • Neuroscience 2019
    Chicago, IL
    Oct 19-Oct 23, 2019
 See all events

       Site map   |   Contact us   |   Conditions of sales   |   Conditions of purchase   |   Privacy policy   |   Diagenode Diagnostics