Diagenode

Human Recombinant Nucleosome

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Catalog Number
Format
Price
C01030101
5 µg
$425.00

Recombinant nucleosome, assembled in vitro by salt dialysis using the 147 bp 601 DNA sequence and the four core histones, H2A, H2B, H3 and H4, produced in E. Coli.

  • Protein description

    The nucleosome is the smallest part of the chromosome. It consists of two core histones of each class H2A, H2B, H3 and H4 which assemble and are wrapped around 146 base pairs of DNA. Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They pack the DNA into tight masses of chromatin. Histones are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histone tails undergo numerous post-translational modifications, which either directly or indirectly alter chromatin structure to facilitate transcriptional activation or repression or other nuclear processes.

     

     

  • Quality control

    Figure 1.
    Native page of the human recombinant nucleosome (lane 2). Lane 1 shows the 147 bp 601 DNA sequence.

  •  Documents
    C01030101 human recombinant nucleosome DATASHEET
    tds of C01030101 human recombinant nucleosome
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  •  Publications

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Events

  • Danish RNA Society's 7th Annual Meeting on RNA
    Aarhus, Denmark
    Oct 11, 2022
  • ASHG 2022
    Los Angeles, California, USA
    Oct 25-Oct 29, 2022
  • International Conference on Epigenetics and Bioengineering 2022
    Houston, Texas, USA
    Oct 27-Oct 29, 2022
 See all events

News

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