Diagenode

Reagents

Proteins

                                      

Diagenode now offers a broad range of tools to study nucleosomes and histones, the structural and functional units of chromatin. We provide solutions for any architectural level of regulation with the best quality recombinant human histones, native or recombinant nucleosomes.

These new tools are the easiest, quickest and most effective way to study in vitro histone post-translational modifications, nucleosome variants, nucleosome distribution and general chromatin structure. In addition, they allow you to perform enzyme activity assays or drug screening.

We offer also a full list of synthetic peptides and recombinant proteins to perform your control experiments. 

Recombinant histone proteins

Cat. No.ProductFormatPrice
C23010016 Recombinant H3.1 Core Histone
Octamer containing 2 units of each full length recombinant histone H3.1, H4, H2A and H2B, produced in E. coli.
25 µg $340.00
C23010017 Recombinant H3.3 Core Histone
Octamer containing 2 units of each full length recombinant histone H3.3, H4, H2A and H2B, produced in E. coli.
25 µg $340.00
C23010001 Recombinant Histone H2A
Full length recombinant histone H2A, produced in E. coli.
100 μg $230.00
C23010010 Recombinant Histone H2A-H2B dimers
Dimer of full length N-terminal Flag tagged recombinant histone H2A and N-terminal His tagged recombinant histone H2B, produced in E. coli.
50 µg $340.00
C23010005 Recombinant Histone H2A.X
Full length recombinant histone H2A.X, produced in E. coli.
100 μg $230.00
C23010006 Recombinant Histone H2A.Z
Full length recombinant histone H2A.Z, produced in E. coli.
100 μg $230.00
C23010012 Recombinant Histone H2A.Z-H2B dimers
Dimer of full length N-terminal Flag tagged recombinant histone H2A.Z and N-terminal His tagged recombinant histone H2B, produced in E. coli.
50 µg $340.00
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Recombinant non-histone protein

Cat. No.ProductFormatPrice
C23010114 Human Recombinant His- and FLAG-tagged full-length DNMT1
Full-length human recombinant DNMT1 (residues 2-1616 (C-terminus); Genbank Accession # NM_001379) expressed in Sf9 insect cells with an N-terminal His-tag an...
25µg at 0,5µg /µl $350.00
C23010113 Recombinant Biotinylated-ubiquitin
Full length recombinant Ubiquitin, produced in E; coli and biotinylated in vitro.
25 µg $230.00
C23010104 Recombinant human Asf1a
Full length recombinant human N-terminal GST tagged ASF1a (Anti-Silencing Function 1A Histone Chaperone) protein, produced in E. coli.  
25 µg $230.00
C23010105 Recombinant human Asf1b
Full length recombinant human N-terminal GST tagged ASF1b (Anti-Silencing Function 1B Histone Chaperone) protein, produced in E. coli.
25 µg $230.00
C23010101 Recombinant human Hp1 alpha (CBX5)
Full length recombinant human N-terminal His tagged HP1a (Heterochromatin Protein 1 Homolog Alpha) protein, produced in E. coli.
25 µg $230.00
C23010102 Recombinant human Hp1 beta (CBX1)
Full length recombinant human N-terminal His tagged HP1b (Heterochromatin Protein 1 Homolog Beta) protein, produced in E. coli.
25 µg $230.00
C23010103 Recombinant human Hp1 gamma (CBX3)
Full length recombinant human N-terminal His tagged HP1g (Heterochromatin Protein 1 Homolog Gamma) protein, produced in E. coli.  
25 µg $230.00
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Nucleosomes

Cat. No.ProductFormatPrice
C01030102 Human Native Nucleosome
Human native nucleosomes purified from HeLa cells, digested with micrococcal nuclease.
20 µg $360.00
C01030101 Human Recombinant Nucleosome
Recombinant nucleosome, assembled in vitro by salt dialysis using the 147 bp 601 DNA sequence and the four core histones, H2A, H2B, H3 and H4, produced in E....
5 µg $395.00

Peptides

Cat. No.ProductFormatPrice
C16000119 ACTL6B peptide
Synthetic peptide:  human ACTL6BSynthetic peptide containing a sequence from the central part of human ACTL6B .This peptide was used as immunogen t...
50 µg/50 µl $95.00
C16000094 BRD2 peptide
Synthetic peptide containing a sequence from the central part of the mouse BRD2 protein. This peptide was used as immunogen to raise the Diagenode crude ser...
50 µg/50 µl $95.00
C16000077 DNMT1 peptide
Synthetic peptide: mouse DNMT1  Synthetic peptide corresponding to the N-terminal region of mouse DNMT1. This peptide was used as immunogen to raise t...
50 µg/50 µl $95.00
C16000095 DNMT2 peptide
Synthetic peptide containing a sequence from the N-terminal part of the mouse DNMT2 protein.  This peptide was used as immunogen to raise the Diagenode...
50 µg/50 µl $95.00
C16000085 DNMT3A peptide
Synthetic peptide: human DNMT3A Synthetic peptide corresponding to amino acids 92 to 106 of human DNMT3A. This peptide was used as immunogen to rai...
50 µg/50 µl $95.00
C16000084 DNMT3A peptide
Synthetic peptide: human DNMT3A  Synthetic peptide corresponding to amino acids 44 to 58 of human DNMT3A. This peptide was used as immunogen to raise ...
50 µg/50 µl $95.00
C16000086 DNMT3A peptide
Synthetic peptide: human DNMT3A Synthetic peptide corresponding to amino acids 107 to 121 of human DNMT3A. This peptide was used as immunogen to ra...
50 µg/50 µl $95.00
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