Expertise | Sonication

Most cited ultrasonicator

Parallel-processing Ultrasonicators with Adaptive Cavitation Technology

Diagenode's Bioruptor® ultrasonicator devices are engineered to deliver highly-controlled ultrasonic energy to biological or chemical samples using ACT (Adaptive Cavitation Technology). ACT is a non-contact, parallel-processing and isothermal technology.

Bioruptor® is the most popular brand in the Epigenetic and Next-Generation Sequencing communities with several hundred citations in peer-reviewed journals. Our instruments provide processing performance and recovery unmatched by any other sample preparation methodology. ACT allows to standardize sample prep for a range of applications including: DNA shearing for Next-Generation Sequencing, chromatin shearing, nucleic acids or protein extraction, cell lysis, nanotubes generation, and more.

The table below will help you to choose the best Bioruptor® for your applications.

Product Specifications Applications & Performance Features
Bioruptor® Pico
Advanced shearing device
All-in-one solution with advanced timing control & regulated cooling.
Sample size : 5 µl – 2 ml
  • Next-Gen Seq
    (5 – 100 µl)
  • Chromatin shearing
    (10 µl – 2 ml)
  • RNA shearing
  Good Best
Chromatin shearing
DNA & RNA shearing
Throughput
Consistency
Thermo-control
Processing time
Programming
  • All in one solution
  • Simultaneous sonication of
    6 – 12 samples
  • Small & light
  • Easy-to-use & install
  • Temperature-controlled
  • No soundproof box
Bioruptor® Plus
Advanced shearing device
Advanced timing control & regulated cooling.
Sample size: 100 µl – 20 ml
  • Chromatin shearing
  • DNA shearing
  • Cell & Tissue disruption
  • Others
  Good Best
Chromatin shearing
DNA shearing
Cell & Tissue disruption
Throughput
Consistency
Thermo-control
Processing time
Programming
  • All in one solution (optional for EU)
  • Simultaneous sonication of
    3 – 12 samples
  • Easy-to-use & install
  • Temperature-controlled (optional for EU)
Bioruptor® Standard
Basic shearing device
Basic timing control & cooling (continuous valve or crushed ice).
Sample size: 100 µl – 20 ml
  • Chromatin shearing
  • DNA shearing
  • Cell & Tissue disruption
  • Others
  Good Best
Chromatin shearing
DNA shearing
Cell & Tissue disruption
Throughput
Consistency
Thermo-control
Processing time
Programming
  • Simultaneous sonication of
    3 – 12 samples
  • Easy-to-use & install
  • Temperature-controlled (optional)

New! Thermo-Control Device

  • Smaller device
  • Lighter
  • Water drain
  • Easy control of water level
  • More fancy features

New! Single Cycle Valve

  • Easy set-up
  • Compact design

 

Compatible with Bioruptor® : Plus (UCD-300) or Pico (B01060001)

 

>> More info about Diagenode' Ultrasonicators