Bioruptor® in Action Video
Expertise | Sonication
Most cited ultrasonicator
Parallel-processing Ultrasonicators with Adaptive Cavitation Technology
Diagenode's Bioruptor® ultrasonicator devices are engineered to deliver highly-controlled ultrasonic energy to biological or chemical samples using ACT (Adaptive Cavitation Technology). ACT is a non-contact, parallel-processing and isothermal technology.
Bioruptor® is the most popular brand in the Epigenetic and Next-Generation Sequencing communities with several hundred citations in peer-reviewed journals. Our instruments provide processing performance and recovery unmatched by any other sample preparation methodology. ACT allows to standardize sample prep for a range of applications including: DNA shearing for Next-Generation Sequencing, chromatin shearing, nucleic acids or protein extraction, cell lysis, nanotubes generation, and more.
"Because of its easy usage and robust technology, I use the Bioruptor for all sonication applications, e. g. cell disruption, DNA shearing and Chromatin immunoprecipitation. I like that I can process several samples at once without overheating due to the thermo-cooling system, thus increasing reproducibility and speeding up my experiments."
Dr. Holger Bierhoff, Molecular Biology of the Cell II (A030), Prof. Dr. Ingrid Grummt's lab,
German Cancer Research Center, Heidelberg, Germany
"The Bioruptor®* NGS is a robust user-friendly sonication system that is key for both reproducible chromatin shearing and DNA shearing. The Bioruptor® NGS consistently delivered optimal DNA shearing that was critical in generating homogeneous sequencing libraries for our experiments. We also observed excellent chromatin shearing results that were crucial for our epigenetic mapping projects."
Dr. Sascha Tierling, Departement of Genetics and Epigenetics, Prof. Dr. Jörn Walter's lab,
Universität des Saarlandes, Germany
The table below will help you to choose the best Bioruptor® for your applications.
New! Thermo-Control Device
- Smaller device
- Water drain
- Easy control of water level
- More fancy features
New! Single Cycle Valve
- Easy set-up
- Compact design
Compatible with Bioruptor® : Plus (B01020001) or Pico (B01060001)