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Chromatin shearing optimization kit - Medium SDS

It has been described widely that detergents (e.g. SDS) are essential for successful chromatin shearing. Diagenode proposes therefore three kits with different SDS concentrations (< 0.1%, 0.5% and 1%) that fit your personal workflow. These kits are compatible with the iDeal ChIP-seq kit, the HighCell# ChIP kit and the LowCell# ChIP kit respectively, which allows you to first optimize your chromatin shearing before performing the ChIP using one of the three mentioned ChIP kits.


Chromatin shearing optimization kit - Medium SDS AA-002-0100 100 million cells 140 $

  • Obtain perfect fragment size for high quality ChIP
  • Get consistent results from different samples and runs
  • Choose your kit for your specific experimental need

It has been described widely that detergents (e.g. SDS) are essential for successful chromatin shearing. Diagenode proposes therefore three kits with different SDS concentrations (< 0.1%, 0.5% and 1%) that fit your personal workflow.

Chromatin Shearing Optimization kit
Low SDS

For ChIP-seq
Chromatin Shearing Optimization kit
Medium SDS
Chromatin Shearing Optimization kit
High SDS
SDS concentration < 0.1% 0.5% 1%
Nuclei isolation Yes Yes No
Allows for shearing of... cells 100 million cells 100 million cells 100 million cells
Corresponding to shearing buffers from iDeal ChIP-seq kit HighCell# ChIP kit LowCell# ChIP kit

Chromatin shearing