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Ago (Argonautes) monoclonal antibody
Description
Members of the Argonaute (Ago) protein family are central to RISC function. Argonaute proteins bind to mature microRNA (miRNAs) and short interfering RNAs (siRNAs) and form the core components of effector complexes that mediate miRNA and siRNA function. Argonautes are needed for miRNA-induced silencing and contain two conserved RNA binding domains: a PAZ domain that can bind the single stranded 3’ end of the mature miRNA and a PIWI domain that structurally resembles ribonuclease-H and functions to interact with the 5’ end of the guide strand.
| Ago (Argonautes) monoclonal antibody | MAb-167-100 | 100 µg / 100 µl | 420 $ |  |
| Ago (Argonautes) monoclonal antibody | MAb-167-050 | 50 µg / 50 µl | 240 $ | |
Description
Purified monoclonal antibody prepared by immunizing mice with recombinant human Ago2 protein (GST fusion protein containing amino acids 47–879 of hAgo2).
Clone: 2A8
Specificity
Human, Mouse, other mammals (wide range): positive. The 2A8 monoclonal antibody recognizes all 4 human and mouse Ago proteins while having higher affinity for Ago2.
Concentration: 1 µg / µl
Source: mouse
Type: monoclonal
Purity
Monoclonal antibody in PBS containing 0.05% azide; affinity purified using Protein A.
Storage
Store at -20°C; for long storage, store at -80°C. Avoid multiple freeze-thaw cycles.
Precautions
This product is for research use only. Not for use in diagnostic or therapeutic procedures.
RIP - HITS CLIP - IHC - IF - WB
