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5-hmC monoclonal antibody (rat)
Description
One of the only two monoclonal antibodies raised against 5-hydroxymethylcytosine (5-hmC). 5-hmC is a recently discovered DNA modification which results from the enzymatic conversion of 5-methylcytosine into 5-hydroxymethylcytosine by the TET family of oxygenases. Preliminary results indicate that 5-hmC may have important roles distinct from 5-methylcytosine (5-mC). Although its precise role has still to be shown, early evidence suggests a few putative mechanisms that could have big implications in epigenetics.
| 5-hmC monoclonal antibody (rat) | MAb-633HMC-100 | 100 µg / 64 µl | 825 $ |  |
| 5-hmC monoclonal antibody (rat) | MAb-633HMC-050 | 50 µg / 32 µl | 490 $ | |
| 5-hmC monoclonal antibody (rat) - sample size | MAb-633HMC-020 | 20 µg / 13 µl | 95 $ | |
Specificity
Human, Mouse, other (wide range): positive
Applications
hMeDIP
Dot blot
IF (Immunofluorescence)
IHC (Immunohistochemistry)
Concentration: 1.6 µg/µl
Source: Rat
Type: monoclonal
Purity
Protein A/G affinity purified monoclonal antibody in PBS containing 0.05% azide.
Storage
Store at -20°C; for long storage, store at -80°C. Avoid multiple freeze-thaw cycles.
Precautions
This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Application key
ChIP-seq = Chromatin Immunoprecipitation sequencing; ChIP = Chromatin Immunoprecipitation; hMeDIP-seq = Hydroxymethylated DNA Immunoprecipitation sequencing; hMeDIP = Hydroxymethylated DNA Immunoprecipitation; MeDIP-seq = Methylated DNA Immunoprecipitation sequencing; MeDIP = Methylated DNA Immunoprecipitation; WB = Western blot; EIA/ELISA = Enzyme immunoassay/ Enzyme-linked immunosorbent assay; EMSA = Electrophoretic Mobility Shift Assay; FACS = Flow Cytometry; IF = Immunofluorescence; IHC = Immunohistochemistry; FACS/Flow cytometry
hMeDIP - Dot blot - IF - IHC
